La lentiginosis unilateral parcial es un trastorno pigmentario poco común, caracterizado por la agrupación unilateral de numerosas manchas marrones que . Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal. Partial unilateral lentiginosis colocalized with naevus depigmentosus. S. I. In. Department of Dermatology, Ajou University School of Medicine.

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Melanocytic Nevi – Partial Unilateral Lentiginosis

Moreover, the patient had a large speckled lentiginous nevus involving the left side of her trunk, and her father showed a similar skin disorder on his left buttock.

It is more common in white skin and rare in black skin. Use of the internet or email is for your convenience only, and by using them, you assume the risk of unauthorized use. Unilatrral simplex is a small well-delimited pigmented macula entailed by the presence of an increased number of isolated melanocytes alongside the dermoepidermal junction, mainly at the sides and bases of elongated and thin interpapillary cones.

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There are exceptional clinical case reports with eyes involvement and nevus of Ota, among others [ 23 – 26 ]. In Partial Unilateral Lentiginosis, small brown melanocytic nevi develop on one half of the body. Statement of Ethics Informed consent was obtained from the patient for being included in this case report.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. From Monday to Friday from 9 a. Discussion PUL have been reported under various names, including unilateral lentigines, lentiginous mosaicism, segmental lentiginosis, zosteriform lentiginous naevus, and agminated lentiginosis [ 3 ].


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Lentiginosis unilateral parcial. | Actas Dermo-Sifiliográficas (English Edition)

Clinical manifestations and treatment response of the patient. Informed consent was obtained from the patient for being included in this case report. Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling. YAG laser with low pulse energy. Request Full Text Paper. Happle R Nevus spilusmaculosus vs. The term lentiginosis is applied when the lentigines are present in great number with distinct distribution.

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Because mature melanosomes accumulate in the dendrites of melanocytes, the selective photothermolytic effect of the laser can be focused intensively on dendrites. National Center for Biotechnology InformationU.

No claim or opinion on these pages is intended to be medical advice or to replace a one-on-one relationship with a qualified health care professional. There is a hypothesis that LUP may represent a mosaicism of a generalized form of lentiginosis with melanocytic proliferation likewise the LEOPARD syndromeforming real lentigos simplex and eventually may be subject to malignant transformation [ 2 ].

It is convenient to perform complementary exams which should include routine biochemistry, thyroid profile, FSH and LH, and to refer to evaluations by a Neurologist, Oftalmologista, Cardiologist and Gastroenterologist, in lentiginpsis to detect eventual associations [ 27 ].

Opinions were requested from Gastroenterology, which did not find a polyposis syndrome, removed lentigknosis adenoma with low degree of atypia and indicated a new colonoscopy in three years; and to Ophthalmology, which did not detect Lisch nodule, or hyperpigmentation of the retina.

At dermatologic examination, small brownish macules were observed on the back of the right hand, right cervical region, right upper chest, right lower lip and right forehead up to the medial line, respecting the upper right half Figures There was no family history of similar pigmented lesions or personal history of neurological problems.


It is also possible that the resulting metabolites from the arachidonic acid pathway and histamine from mast cells may affect melanogenesis [ 14 ], thus resulting in PIH. If appropriate measures are taken to monitor patient response during and after the procedure, low-fluence 1,nm QS Nd: If the distribution of the lesion is limited to a single dermatome, it may be confused with nevus spilus, also known as lentiginous nevus or zosteriform nevus [ 45 ].

This website is provided for information and education purposes only and is not intended to offer specific medical or surgical advice to anyone. No guarantees or warranties are made lentiginozis any of the information contained herein.

Please type a message to the paper’s authors to explain your need for the paper. Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling. J Am Lentlginosis Dermatol Careful monitoring of patient response may prevent such side effects. These cytokines activate melanocytes and increase melanin synthesis in the melanosomes, therefore causing PIH [ 101112 ].

The basal layer is usually hyperpigmented and foci of melanic pigment can be found in the horny layer. Pemphigus Vegetans in the Inguinal Folds. J Electron Microsc Tokyo ; Parciao Eur Acad Dermatol Venereol.

When affecting the lips, the Peutz-Jeghers syndrome should be investigated [ 11 ]. These lesions were taken to be unrelated to the patient’s segmental neurofibromatosis 1.